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AForge.NET is a completely free and open-source toolkit that includes a large number of computer vision, image processing, and machine learning algorithms.
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My suggestion is to take a look at ResourceSubscription manager.
Here's a link to the readme, and here's a link to the website.
They both come from Adobe but are very well developed and used on a daily basis. It's a standalone program, but the team is constantly updating it to be much better. And they are always adding new features, so it's a perfect tool for people like you and me who want to be creative and have a unique user interface.
The license is free for personal use and you can even pay a yearly fee for commercial use.
They also have a website where you can see what features they added recently. This is pretty helpful to keep track of what new features they add.
Mutation analysis of the four TSS of STXBP1 in autism spectrum disorder and intellectual disability.
Autism spectrum disorder (ASD) and intellectual disability (ID) are genetically heterogeneous. Recently, frameshift and nonsense mutations have been identified in TSC1, TSC2, TUBB3, and STXBP1 genes in ASD/ID patients. STXBP1 has four transcription start sites (TSSs), which have been investigated for mutations in ASD/ID cases. One (TSS1) is on the non-coding region, the other three are exons. A TSS1 mutation was found in a male with ASD/ID, but the other three exonic mutations were not previously reported. Mutations were not identified in the coding region of STXBP1 in exon 3, 4, and 5. In contrast, a nonsense mutation was found in the coding region of exon 4, which leads to the creation of a premature stop codon and the loss of the C-terminal part of the protein. A missense mutation was found in the coding region of exon 1, which results in the substitution of aspartic acid for glycine at position 20. The mutation was also identified in the ASD/ID family. The mutation was located within the regulatory region of STXBP1, which has been previously implicated in the development of ASD/ID. Although many ASD/ID cases are unknown, our data suggest that STXBP1 gene mutations account for approximately 2-3% of the cases.The present invention relates to an optical lens, especially for spectacle frames, and a method of manufacturing such an optical lens.
For the purpose of the present invention the term
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